Clinical observation of treatment through intrarenous thrombolysis with urokinase for patients with acute cerebral infarction at an early stage
- VernacularTitle:急性脑梗死早期尿激酶静脉溶栓治疗临床观察
- Author:
Ping LIU
;
Xiaohong LI
;
Qinjun GAO
- Publication Type:Journal Article
- Keywords:
Acute cerebral infarction Urokinase Intravenous thrombolysis
- From:
Chinese Journal of Practical Internal Medicine
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To evaluate efficacy of intravenous thrombolysis with urokinase(UK) for treatment of patients with acute cerebral infarction (ACI)at early stage.Methods 76 patients with ACI onseting within 6 hours were randomizd into two groups,UK regime group and control group.UK group was given included 250 000 units UK IV injection and then 1500 000 units IV dripping.Neurologic defect scoring system was used to evaluate patients' responses at admission,and 24 hours,one week,two weeks as well as 4 weeks after treatment.Results Significant improvements of neurologic defect scorings happened in both groups between 24 hours and 4 weeks after treatment.As for the improvement of neurologic defect scoring,there were significant defferences between both groups at 24 hours,1st week,2nd weeks and 4th weeks of post dosing respectively(P