Susceptibility testing of yeasts to combination of amphotericin B and 5-flucytosine in vitro according to M27-A method
- VernacularTitle:两性霉素B和5-氟胞嘧啶的体外联合药敏试验
- Author:
Hong CHEN
;
Hai WEN
;
Hong XU
;
Wanqing LIAO
- Publication Type:Journal Article
- Keywords:
Candida;
Cryptococcus neoformans;
microbial sensitivity tests;
amphotericin B;
5-flucytosine
- From:
Academic Journal of Second Military Medical University
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
This article is to study the interaction between amphotericin B and 5-flucytosine to yeasts in vitro. The checkerboard microdilution method was applied to study in vitro interaction according to M27-A method of NCCLS. Twenty-eight strains of yeasts were used for combination study. Compared with the single agents,there were significant reductions in the geometric mean of the minimal inhibitory concentration of the combination(P