DYNAMIC STUDY OF SERUM IAP AND T-LYMPHOCYTES rDNA TRANSCRIPTION ACTIVITY IN PERIOPERATIVE PERIOD IN PATIENTS WITH PANCREATIC CANCER
- VernacularTitle:胰腺癌围手术期IAP和T淋巴细胞rDNA转录活性的动态观察
- Author:
Wen HUANG
;
Jide WANG
;
Gan XU
- Publication Type:Journal Article
- Keywords:
pancreatic neoplasms;
immunosuppressive acidic protein (IAP);
T lymphocytes;
rDNA transcription activity
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the changes in serum immunosuppressive acidic protein (IAP) and T lymphocytes rDNA transcription activity in peripheral blood of patients with pancreatic cancer before and after operation. The level of IAP and T lymphocytes rDNA transcription activity in peripheral blood of 58 patients with pancreatic cancer were measured before and after opreration by one directional immunodiffusion test and a cell image analysis of Ag NORs, respectively, and the results were compared with that of healthy controls. The level of IAP was higher while T lymphocytes rDNA transcription activity was lower before operation compared with healthy controls( P 0 05). The levels of IAP and T lymphocytes rDNA transcription activity were closely related to tumor invasion, metastasis and clinical stages (TNM). Serial determination of the levels of IAP and T lymphocytes rDNA transcription activity might serve as an important index for evalution of tumor invasion and metatasis, and also prognosis for the patients with pancreatic cancer
