Effect of NIP regime in treatment of non-small cell lung cancer
- VernacularTitle:NIP方案治疗晚期非小细胞肺癌的近期疗效观察
- Author:
Gang FENG
;
Ping LI
;
Bin ZHANG
- Publication Type:Journal Article
- Keywords:
non small cell lung cancer;
chemotherapy;
vinorelbine;
ifosfomide;
cisplatin
- From:
Academic Journal of Second Military Medical University
1981;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
This research is to investigate the effect of NIP regime in the treatment of non small cell lung cancer (NSCLC) and its side effects.Thirty two patients with NSCLC (stageⅢ 28 cases, include Ⅲa 6 cases and Ⅲb 22 cases, stageⅣ 4 cases) received chemotherapy regime NIP.Vinorelbine(NVB)25 mg/m 2 V.D,first day and eighth day ;Ifosfomide(IFO) 1.6 g mg/m 2 V.D, from first day to third day; Cisplatin(DDP)25 mg/m 2 V.D,from first day to third day.Four weeks was a cycle, every patients was given 2 cycles. RR was 53.13%(CR 1/32,PR 16/32,SD 4/32,PD 9/32). Main side effect was mylosuppression.NIP regime is effective and safe for patients with advanced NSCLC.