Three Cases of Diffuse Large B-Cell Lymphoma Presenting as Primary Splenic Lymphoma.
10.3349/ymj.2005.46.5.703
- Author:
Ja Kyung KIM
1
;
Jee Sook HAHN
;
Gwi Eon KIM
;
Woo Ick YANG
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. medi@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Lymphoma;
spleen;
non-Hodgkin's;
lymphoma
- MeSH:
Splenic Neoplasms/*diagnosis/pathology/therapy;
Splenectomy;
Middle Aged;
Male;
Lymphoma, Large-Cell, Diffuse/*diagnosis/pathology/therapy;
Lymphoma, B-Cell/*diagnosis/pathology/therapy;
Humans;
Female
- From:Yonsei Medical Journal
2005;46(5):703-709
- CountryRepublic of Korea
- Language:English
-
Abstract:
Primary splenic lymphoma (PSL) is often defined as generalized lymphoma with splenic involvement as the dominant feature. It is a rare disease that comprises approximately 1% of all malignant lymphomas. We investigated three cases of non-Hodgkin's splenic lymphoma that had different clinical features on presentation. The patients' survival times from diagnosis ranged from 59 to 143 months, without evidence of relapse after splenectomy and chemotherapy, with or without radiotherapy. This data suggest that PSL is potentially curable. Further studies are needed to evaluate the impact that different treatment modalities without splenectomy have on patient survival.
