STUDIES ON CURATIVE EFFECT OF MELATONIN ON AGRYPNIA IN MIDDLE-AGED AND ELDERLY PEOPLE AND ITS SAFETY
- VernacularTitle:褪黑素对中老年人失眠的疗效及安全性研究
- Author:
Ying ZHAO
;
Ying LIU
;
Yongquan SHI
- Publication Type:Journal Article
- Keywords:
melatonin;
sleep initiation and maintenance disorders;
treatment outcome;
reliability
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Elderly agrypnia patients were given with different doses of melatonin. Patients′ falling a sleep time, coming into effect time, sleep lasting time and adverse effect of melatonin were observed to study the effect and safety of melatonin on elderly agrypnia patients. The results showed melatonin could effectively improve the agrypnia suffered by elderly patients. Patients′ falling a sleep time was shortened and sleep lasting time prolonged after taking melatonin. The effect of melatonin increased along with increase of its dose.There were no adverse effects observed. Our study indicates that melatonin has a good safety profile and significant effects on agrypnia suffered by elderly patients.
