Value of heart-type fatty acid-binding protein for early diagnosis of acute myocardial infarction
10.3969/j.issn.1673-4130.2014.13.022
- VernacularTitle:心脏型脂肪酸结合蛋白对早期急性心肌梗死的诊断价值
- Author:
Chaomin CAI
;
Yunsheng PENG
;
Minggang CHENG
;
Xiangping LIU
;
Yuzhong XU
;
Guoqiang YE
- Publication Type:Journal Article
- Keywords:
heart-type fatty acid-binding protein;
myocardial infarction;
troponin I
- From:
International Journal of Laboratory Medicine
2014;(13):1718-1719,1721
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of heart-type fatty acid-binding protein in the diagnosis of early myocardial infarc-tion.Methods In 186 cases of suspected acute myocardial infarction due to chest pain,chest tightness for 3 h,plasma CK-MB, troponin-I(CTn-I)and heart-type fatty acid-binding protein(H-FABP)were detected.The sensitivity and specificity in diagnosing early myocardial infarction were compared among 3 kinds of indexes.Results Compared with the non-infarction group and the con-trol group,plasma CK-MB,CTn-I and H-FABP in the acute myocardial infarction group were significantly increased (P <0.05 );compared with CK-MB and CTn-I,the sensitivity of H-FABP to the diagnosis of acute myocardial infarction within 3 h was higher, but its specificity was lower than that of CTn-I and higher than that of CK-MB.Conclusion For the patients with acute myocardial infarction within 3 h after onset,detecting H-FABP can increase the diagnostic rate of early myocardial infarction to a certain extent.
