Expression and clinical significance of ADA,CRP and CEA in pulmonary and extrapulmonary tuberculosis
10.3969/j.issn.1671-8348.2014.17.010
- VernacularTitle:肺结核和肺外结核患者ADA、CRP、CEA的表达及临床意义
- Author:
Jihai XIAO
- Publication Type:Journal Article
- Keywords:
denosine-deaminase;
C-reactive-protein;
carcinoembryonic-antigen;
pulmonary-tuberculosis;
extrapulmonary-tuberculosis
- From:
Chongqing Medicine
2014;(17):2137-2138,2141
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of adenosine deaminase (ADA),C-reactive protein (CRP)and carcinoembry-onic antigen (CEA)in the diagnosis of pulmonary tuberculosis(TB)and extrapulmonary tuberculosis (EPTB).Methods ADA was measured with the liquid dual reagent velocity method,CRP with the gold-labeled immunization test and CEA with ELISA.90 a-dults were as controls,94 cases of pulmonary TB as the pulmonary TB group and 73 cases of EPTB as the EPTB group.The ADA, CRP and CEA levels were compared among 3 groups.Results The levels of ADA,CRP and CEA in the pulmonary TB group and the EPTB group were (50.1±24.4)U/L,(53.6±21.3)mg/L and (8.7±3.4)μg/L;(49.2±23.5)U/L,(49.8±19.8)mg/L and (8.5±3.3)μg/L respectively,which were significantly higher than (17.1±5.1)U/L,(8.7±2.5)mg/L and (5.4±2.3)μg/L in the control group,the differences had statistical significance (P<0.05).The positive rates of ADA and CRP were 91.5% and 89.4% in the pulmonary TB group and 84.9% and 91.8% in the EPTB group,which were higher than 2.2% and 1.1% in the con-trol group,the difference was statistically significant (P<0.05).Conclusion The measurement of ADA,CRP and CEA is of high clinical value in the diagnosis and differential diagnosis of pulmonary TB and EPTB.
