Comparison the diagnosis of chronic hepatic fibrosis and cirrhosis with ADC value of the liver and the liver-spleen volume ratio examined by MR
10.3969/j.issn.1002-1671.2014.07.019
- VernacularTitle:肝ADC值及MR肝脾体积比值对肝纤维化、肝硬化诊断价值的比较
- Author:
Hao YU
- Publication Type:Journal Article
- Keywords:
liver fibrosis;
magnetic resonance imaging;
liver and spleen volume ratio
- From:
Journal of Practical Radiology
2014;(7):1141-1143,1153
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship and compare the diagnosis in chronic hepatic fibrosis and cirrhosis between liver ADC value and the liver spleen volume ratio changes by MR.Methods The obj ect included 3 1 cases of chronic hepatic fibrosis, cirrhosis and 14 cases of control group.The liver ADC value (b=800 s/mm2 )and the liver spleen volume ratio in different fibrosis stages were measured.Analysis of variances was performed to compare the difference between the two groups.Results The right lobe of liver ADC value and the liver spleen volume ratio in each group was significant (P<0.01).With the increase of fibrosis score,liver ADC was correlated negatively.From normal to mild cirrhosis (S1-S2),the total liver volume increased progressively. From severe hepatic fibrosis to advanced cirrhosis (S3-S4),it decreased slowly and spleen volume increased gradually along as cir-rhosis degree,while the liver spleen volume ratio correspondingly decreased.Area under the curve (AUC)in the group of liver ADC value was 0.789,sensitivity was 0.806,and specificity was 0.857.The group of liver spleen volume ratio AUC was 0.744,sensi-tivity was 0.742,and specificity was 0.714.Conclusion The correlation of the two methods for evaluating the effectiveness of liver fibrosis and cirrhosis are both significant.Whereas,ADC value was better for liver fibrosis,which is the best method for diagnosis of early liver fibrosis.
