SIGNIFICANCE OF IMMUNOCYTES IN PATHOGENESIS OF AUTOIMMUNE HEPATITIS
- VernacularTitle:免疫活性细胞在自身免疫性肝炎发病机制中的意义
- Author:
Wangxia LIU
;
Jingmin ZHAO
;
Fushen WANG
- Publication Type:Journal Article
- Keywords:
hepatitis, autoimmune;
lymphocytes;
dendritic cells
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the significance of immunocytes in pathogenesis of autoimmune hepatitis (AIH), 36 cases of patients with AIH were analyzed. Dendritic cell (DC) and lymphocytes (LC) in the liver tissues were observed with a panel of DC markers and monoclonal antibodies of lymphocyte by the method of immunohistochemistry, and DC was isolated and incubated from peripheral blood from 8 patients who were selected from these 36 patients. The expression of surface markers on DC and lymphocytes and their numbers were detected by using the flow cytometric analysis. The results showed that the expression levels of HLA DR were much higher than those in control groups ( P
