EFFECT OF HIGH ALTITUDE ON EXPRESSION OF TGF-?1 DURING THE HEALING PROCESS OF RADIUS FRACTURE IN RATS
- VernacularTitle:高原环境对大鼠桡骨骨折愈合过程中TGF-?1表达的影响
- Author:
Yonglong CHEN
;
Mingquan LEI
;
Yin LAN
- Publication Type:Journal Article
- Keywords:
high altitude;
fracture healing;
transforming growth factor beta
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the effect of high altitude on the expression of transforming growth factor beta 1 (TGF ?1) during the healing process of radius fracture, a rat radius fracture model was established at a high altitude. The expression of TGF ?1 in callus was detected using of immunohistochemistry method. It was found that the expression of TGF ?1 in the rats of high altitude group were decreased significantly compared with the low altitude group, especially high altitude might affect the on day 3 and week 3 ( P
