THERAPEUTICS EFFECT OF INTRACTABLE SCHIZOPHRENIA BY LESIONING DIFFERENT SUBNUCLEUES OF AMYGDALA AND FRONT PART OF CALLOSAL GYRUS WITH STEREOTACTIC TECHNIQUE
- VernacularTitle:立体定向毁损杏仁核簇不同亚核团和扣带回前区治疗难治性精神分裂症
- Author:
Shuande LI
;
Tao LI
;
Xiaofen WANG
- Publication Type:Journal Article
- Keywords:
schizophrenia;
amygdala;
callosal gyrus;
stereotactic techniques
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate feasibility and effect of schizophrenia treatment by stereotactic lesioning, CRW stereotactic apparatus and PICKER spiral CT were used to define nucleus location and RADONICS radiofrequency instruments were used to lesion different subnucleuses of amygdala and the front part of callosal gyrus. All schizophrenic patients were diagnosed by ICD Ⅲ standards, In cases with one year followup ,the effect were analysed with Global Improvement (GI) scoring. In this group , 21 cases were significantly improved , 8 cases improved, 3 cases slightly improved, 1 case unchanged, and 0 case deteriorated. These results suggest selective lesioning subnucleus of amygdala according to different symptoms of schizophrenia could improve the curative effect of surgical treatment for schizophrenia.
