Diagnosis and treatment of tumor-associated gastrocolic fistula: a report of 4 cases
10.3760/cma.j.issn.1673-4203.2014.08.011
- VernacularTitle:肿瘤相关的胃结肠瘘的诊疗方式的探讨(附4例病例报告)
- Author:
Jun CAI
;
Jie YIN
;
Zhi ZHENG
;
Kangli WANG
;
Zhongtao ZHANG
- Publication Type:Journal Article
- Keywords:
Gastrocolic fistula;
Surgical procedures,operative;
Diagnosis;
Drug therapy,combination
- From:
International Journal of Surgery
2014;41(8):540-544,封3
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnosis and treatment of tumor associated gastrocolic fistula (GCF).Methods The records of the 4 patients with GCF between August 2008 to February 2014 were retrospectively analyzed.Three female and one male patients,those whose average age were 61 years,have been pathologically diagnosed postoperatively as gastrocolic fistula caused by malignant diseases.The main clinical symptoms were diarrhea (3 cases),fecal vomitus (3 cases),weight loss (4 cases),and abdominal pain (4 cases).Positive diagnostic tests for GCF included gastroscope (3 cases),colonoscope (1 case),barium enema (1 case),upper gastrointestinal contrast (2 cases).Results En-bloc resection of the involved gastrocolic region have been performed for all,2 patients underwent radical gastrectomy and colon resection and 2 patients were taken on palliative procedure.Pathology indicated adenocarcinoma all,Immunohistochemical detection for CK20,CDX-2 were applied for identifying the originations of tumors.Delayed gastric emptying and DIC occurred in one patient who died in 3 months after the operation,anastomotic leakages were found in 2 cases.The survival patients were all discharged and taken capecitabine combined with Oxaliplatin for chemotherapy.Conclusions Endaoscopy and gastrointestinal imaging are main evidences for diagnosis of GCF.En-bloc resection of the involved gastrocolic region were recommended,enterostomy was safer than entero-anastomosis in one stage procedure.The originations of tumors may be identifying according to the pathological characteristic and CDX-2,CK20 staining.Adjuvant chemotherapy should be applied.
