Relative studies on anti-?_2-glycoprotein I and extracellular matrix in post-hepatitis B cirrhosis
- VernacularTitle:抗?_2糖蛋白Ⅰ抗体与乙型肝炎后肝硬化细胞外基质的相关性研究
- Author:
Pujun GAO
;
Yunfeng PIAO
;
Xiaocong WANG
- Publication Type:Journal Article
- Keywords:
Anti-?2-glycoprotein I Liver cirrhosis\ Extrallular matrix
- From:
Chinese Journal of Practical Internal Medicine
2000;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between anti-? 2-glycoprotein I(a? 2GPⅠ) and extracellular matrix (ECM) in patients with post-hepatitis B cirrhosis (PHBC).Method The of patients with chronic hepatitis B (CHB) and PHBC were studied for the serum a? 2GPⅠ levels by ELISA with purified ? 2GPⅠ as antigen, and we investigated serum level of collagen IV (IV-C)?hyaluronic acid (HA) and laminin (LN) in these patients.Result High positive rate was observed compared with control group (P