Three dimensional-conformal radiotherapy combined with chemotherapy for locally advanced non-small cell lung cancer
- VernacularTitle:三维适形放射治疗配合化疗治疗局部晚期非小细胞肺癌
- Author:
Qibin SONG
;
Desheng HU
;
Liming XU
;
Changqing LI
- Publication Type:Journal Article
- Keywords:
Carcinoma, non small cell lung / radiotherapy;
Three dimensional conformal radiotherapy;
Carcinoma, non small cell lung / chemotherapy;
Prognosis
- From:
Chinese Journal of Radiation Oncology
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the acute side effects and efficacy of three dimensional conformal radiotherapy(3DCRT) combined with chemotherapy(CT) for locally advanced non small cell lung cancer(LANSCLC). Methods From Sept. 2000 to Dec.2001,24 patients with LANSCLC were treated with three dimensional conformal radiotherapy combined with chemotherapy navelbine+cisplatin NP. Results The overall response rate(CR+PR)was 91.7% for the primary tumor, and 100% for metastatic mediastinal lymph nodes.The leucopenia rate was 95.8%(54.2% grades 3,4). Acute radiation esophagitis occurred in 54.2% of patients(Grades 1,2). Acute radiation pneumonitis was observed in 12.5% of patients (Grades1,2). Conclusions 3DCRT combined with CT is well tolerated in most patients with LANSCLC. Its early responses are milder than the conventional radiotherapy combined with chemotherapy . Remote results await further follow up.
