Clinical efficacy evaluation of mifepristone alone and combined with Gongliuxiao capsule in the treatment of uterine fibroids
- VernacularTitle:米非司酮独用及与宫瘤消胶囊合用治疗子宫肌瘤的效果评价
- Author:
Weijing JIA
;
Jin JIANG
- Publication Type:Journal Article
- Keywords:
uterine fibroids;
mifepristone;
Gongliuxiao capsule;
combination treatment
- From:
Chinese Journal of Biochemical Pharmaceutics
2014;37(4):111-112,115
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate and compare the clinical efficacy of mifepristone alone and combined with Gongliuxiao capsule in the treatment of uterine fibroids.Methods 106 patients with uterine fibroids in Harrison International Peace Hospital from December 2012 to December 2013 were selected.The patients were randomly divided into control group and experimental group(n=53).The former were treated with mifepristone alone while the later were treated with the combination of mifepristone and Gongliuxiao capsule.All the patients were given 2 courses of treatment with 12 weeks for a course.The menstrual phase,volume of menstruation,uterus and the volorne of uterine fibroids before and after the treatment,and the clinical efficacy of both groups were evaluated.All the results were recorded and compared. Results The menstrual phase,volume of menstruation,uterus and uterine fibroids of both groups after the treatment were significantly less than those before treatment (P <0.05 ).And the total effective rate of experimental group was 92.45%,which was significantly higher than 73.58% of control group.Both groups had some mild adverse reactions,which didn’t affect the treatment.Conclusion The combination of mifepristone and Gongliuxiao capsule has a great efficacy in the treatment of uterine fibroids.Compared with the use of mifepristone alone,the combination treatment is much more effective.
