THE EFFECT OF LOCAL APPLICATION OF BFGF AND SUCRALFATE COMBINED WITH CTE ON VIABILITY AND STRETCH-BACK OF EXPANDED SKIN FLAP IN A PIG MODEL
- VernacularTitle:bFGF和硫糖铝对扩张后皮瓣成活长度及回缩率影响的实验研究
- Author:
Yalan HU
;
Shuzhong GUO
;
Kaihu LU
- Publication Type:Journal Article
- Keywords:
fibroblast growth factor, basic;
sucralfate;
dilatation;
surgical flaps
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the effect of bFGF and sucralfate on the improvement of the quality of expanded skin flap, white piglets were employed to establish a continuous tissue expansion model. They were randomly divided into 3 groups: group 1: both bFGF and sucralfate were injected; group 2: both bFGF and normal saline was injected; and group 3(the control group):only normal saline was injected. Three days after completion of the expansion ,normal and expanded skin flaps were created at random to assess flap viability and stretch back .The results showed that the flap survival length in group 1 was significantly larger than that of the control group and normal random flap( P