Clinical characteristics and prognosis in patients with acute renal failure due to sepsis: a multivariate analysis
- VernacularTitle:败血症并发急性肾功能衰竭患者的临床特点和影响预后的因素
- Author:
Wenxian ZHANG
;
Xun ZHANG
;
Fanfan HOU
- Publication Type:Journal Article
- Keywords:
Renal failure acute;
Sepsis;
Prognosis
- From:
Chinese Journal of Nephrology
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical characteristics and prognostic factors in patients with acute renal failure (ARF) due to sepsis. Methods A case-control retrospective study was carried out in patients with acute renal failure due to sepsis and non-sepsis. Univariate and multivariate logistic regression analysis was performed to find the correlation among prognosis, clinico-biochemical parameters and scoring indexes of APACHE II and ATN-ISI. Results The incidence of septic ARF was 15. 6% in all ARF patients. Multiple organ failure was most common (87.9% ) in these patients with a high mortality (69. 7% ). Single-variable analysis showed that surgery, respiratory failure, hepatic failure, mechanical ventilation, oliguria, coma, multiple organ failure, ARF occurred during ICU stay and chronic health points were factors influencing prognosis. Multivariate logistic regression analysis showed that oliguria, ARF occurred during ICU stay, chronic health points, and multiple organ failure were the independent predictors of hospital mortality. Conclusion Outcome of septic ARF is correlated with factors including oliguria, ARF occurred during ICU stay, chronic health points and multiple organ failure.
