STUDY ON EXPRESSION OF VEGF mRNA IN PULMONARY TISSUES OF TAIL-SUSPENDED RATS DURING SIMULATED WEIGHTLESSNESS
- VernacularTitle:尾悬吊模拟失重大鼠肺组织VEGF mRNA的研究
- Author:
Junfeng WANG
;
Changting LIU
;
Delong WANG
- Publication Type:Journal Article
- Keywords:
simulated weightlessness;
suspension;
vascular endothelial growth factor;
gene;
pulmonary tissues
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the changes of vascular endothelial growth factor mRNA (VEGFmRNA) in pulmonary tissues of tail suspended rats during simulated weightlessness,the experiments were conducted on 40 Spragno Dawley male rats,divided into 4 groups:suspended for 7d,control of 7d and suspended for 21d,control of 21d.Tail suspension(-30?) was used as weightlessness simulation.The condition of VEGFmRNA in pulmonary tissues was examined by hybridization in situ. The results showed that the level of VEGFmRNA in pulmonary tissues of 7d tail suspended rats increased significantly( P
