CORRELATION BETWEEN EXPRESSION OF THREE CELL ADHESION MOLECULES AND CLINICAL PATHOLOGY CHARACTER AND PROGNOSIS IN BREAST CANCER
- VernacularTitle:3种细胞粘附分子表达与乳腺癌临床病理特征和预后的关系
- Author:
Huaping GU
;
Peizhong SHANG
;
Canrong NI
- Publication Type:Journal Article
- Keywords:
breast neoplasms;
cell adhesion molecules;
neoplasm metasthsis prognosis
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the relationship of expression of sialyl Lewis X (SLeX) antigen,CD44v6 and E cadherin(ED) with staging,infiltration,node metastasis and prognosis in breast cancer, immunohistochemical method was used to detect their expression in 94 cases of breast cancer.The positive expression of SLeX,CD44v6 and the negative expression of ED were positively correlated with the grading, clinical staging, lymph node metastasis recurrence and prognosis of breast cancer.The results demonstrated that the expression of SLeX, CD44v6 and ED as a clinical valuable marker,has a great significance in assessing node metastasis and prognosis.
