Study of risk factors for early interhepatic recurrence and metastasis of hepatocellular carcinoma on CT findings
10.3969/j.issn.1002-1671.2014.05.017
- VernacularTitle:肝细胞癌肝内早期复发转移 CT 表现影响因素研究
- Author:
Shunyu GAO
;
Xiaopeng ZHANG
;
Yong CUI
;
Yingshi SUN
;
Lei TANG
;
Xiaoting LI
;
Jun SHAN
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma;
computed tomography;
prognosis;
recurrence;
metastasis
- From:
Journal of Practical Radiology
2014;(5):783-785,896
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors for early interhepatic recurrence and metastasis of hepatocellular carcinoma (HCC)on CT imaging before treatment.Methods 1 1 5 patients suffered from HCC from July 2003 to January 2009 were retrospec-tively enrolled for reviewing their clinical characteristics and CT signs.The status of metastasis and/or recurrence was followed reg-ularly.Signs on pre-treatment enhanced CT images were measured and analyzed.Analysis of variance and independent sampler t test were applied for Univariate survival analysis.Then multivariate analysis was carried out by the Logistic regression,Lon rank meth-od,and p-value < 0.05 was defined to be statistically significant.Results The early interhepatic recurrence and metastasis rate of the study group was 58.26%.With univariate analysis,tumor size,location,extent,capsule,satellite nodule,vascular invasion, AVM and necrosis were the risk factors for early recurrence and metastasis of HCC on pre-treatment enhanced CT imaging (P<0.05).Multi-variable Logistic regression analysis showed that tumor size,satellite nodule,vascular invasion capsule and were independently sig-nificant CT signs for early interhepatic recurrence and metastasis of HCC (P =0.031,0.005、0.037、0.048).Conclusion Pre-treat-ment enhanced CT imaging with HCC was closely related to early interhepatic recurrence and metastasis of the tumor.A tumor of larger size,with satellite nodules,without complete capsule and vascular invasion on CT may predict a tendency to early interhepatic recurrence and metastasis of HCC.
