The clinical application of nerve allograft processed with glycerol
- VernacularTitle:甘油处理的同种异体神经在临床的应用
- Author:
Jinmu LIU
;
Hao PENG
;
Zhilin WANG
- Publication Type:Journal Article
- Keywords:
Glycerol;
Nerve allograft;
Transplantation
- From:
Journal of Clinical Surgery
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To find out easily-processed and longly-preservated nerve allograft transplantation which has not only no-obvious antigenicity,but the integral structure of intermal nerve membrane.Mehtods Acquire the nerve allografts under sterile condition,submerge them into 50 ,70 and 85 percent of glycerol for 3 hours respectively at 37 Centigrade degree,then put them into the containers which contain 85 percent of glycerol. After sealed and preservated at 5 Centigrade degree for 6 weeks,the processed nerves can be used for transplantation.Results 14 nerve allografts processed with glycerol were transplanted in 10 patients with nerve defects varying from 2.5 to 18 cm. After follow-up for 5 to 42 months,the effects were proved to be satisfactory.Conclusion It is obviously effective to transplant nerve allograft processed with glycerol and preservated for 6 weeks for bridging the defects of peripherall nerve through a series of clinical observations.
