EVALUATION OF URINARY PYRIDINOLINE AND DEOXYPYRIDINOLINE RATIO IN DISEASES WITH BONE LOSS
- VernacularTitle:尿吡啶啉/脱氧吡啶啉比值在骨量丢失疾病中的临床意义
- Author:
Zhiwei ZHAN
;
Itsuo YAMAMOTO
;
Rikushi MORITA
- Publication Type:Journal Article
- Keywords:
pyridinoline/deoxypyridinoline ratio;
osteoporosis;
neoplasm metastasis;
arthritis, rheumatoid
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the ratio of urinary pyridinoline (Pyr) and deoxypyridinoline (Dpyr) in diseases with bone loss, urinary Pyr and Dpyr levels were evaluated in 48 cases of osteoporosis, 8 cases of carcinoma with bone metastasis, 6 cases of rheumatoid arthritis, and 78 healthy volunteers. It was found that urinary Pyr and Dpyr increased significantly as compared to those in the control ( P 0 05), while it was dramatically lower in the patients with carcinoma bone metastasis ( P