Observation of montelukast combined with small dose of inhaled corticosteroid in the treatment of cough va-riant asthma

VernacularTitle:孟鲁司特联合小剂量吸入型糖皮质激素治疗咳嗽变异性哮喘观察
Author: Jiaohong MAO ; Hongbing ZHANG ; Lixiang HUANG
Publication Type:Journal Article
Keywords: Montelukast; Glucocorticoids; Variant asthma
From: Chinese Journal of Primary Medicine and Pharmacy 2014;(9):1344-1345,1346
CountryChina
Language:Chinese
Abstract: Objective To study the curative effect of combing montelukast with inhaled corticosteroids in the treatment of cough variant asthma .Methods According to diagnosis standard guideline for diagnosis and treatment of cough in CVA,84 cases of CVA patients were chosen and divided into the treatment group (n=42)and the control group(n=42).The control group were treated with inhaled corticosteroid Budesonide .The treatment group was given monelukast based on the treatment in control group .And the clinical effects of two groups ,recurrence and the lung function index were observed .Results The total efficiency of treatment of the control group was 73.8%,and the treatment group was 95.0%.The total effective rate of observation group was apparently higher than that of the control group(χ2 =6.46,P<0.05).The lung function of the treatment group compared to the control group was significantly increased(t=2.873,P<0.05).Conclusion Montelukast combined with Glucocorticoid in the treatment of CVA can effectively improve the cure rate ,reduce the recurrence ,which can be widely used in clinical treatment .