EFFECT OF ISCHEMIC PRECONDITIONING ON THE EXPRESSION OF HSP-70 MRNA IN POSTISCHEMIC SPINAL CORD OF RABBITS
- VernacularTitle:缺血预处理对缺血再灌注后兔腰髓组织中HSPs-70 mRNA表达的影响
- Author:
Ge MENG
;
Langbiao ZHU
;
Yal ZHAO
- Publication Type:Journal Article
- Keywords:
ischemic precontioning;
spinal cord ischemia;
heat shock proteins 70
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the effect of ischemic preconditioning(IP) on the expression of HSP 70 mRNA in postischemic spinal cord of rabbits, the spinal cord ischemic model was established by inflating the balloon of a 4F Swan Ganz catheter positioned in the abdominal aorta of the rabbits. The rabbits were divided into sham operated group, ischemic group and IP group. The expression of HSP 70 mRNA in postischemic spinal cord was observed by using the method of RT PCR at 4 hours, 2 days and 5 days after spinal cord ischemia respectively. No expression of HSPs 70 mRNA was found in sham operative group. Compared with ischemic group,the expression of HSP 70 mRNA in spinal cord of IP group was strengthened( P
