ACUTE RENAL TRANSPLANT REJECTION DIAGNOSED BY DETERMINATION OF MONOCYTE CHEMOTACTIC PEPTIDE-1 IN URINE
- VernacularTitle:检测尿液MCP-1含量对诊断肾移植后急性排斥反应的意义
- Author:
Xinghui SUN
;
Qiansheng LI
;
Yuhu FANG
- Publication Type:Journal Article
- Keywords:
organ transplantation;
host vs graft reaction;
chemotactic factors
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Monocyte chemotactic peptide 1(MCP 1) is a specific chemotactic and activating factor for monocytes in acute renal transplant rejection. The present study was to diagnose aimed at diagnosing acute renal transplant rejection by determination of MCP 1 concentration in urine of kidney recipients by avidin biotin complex enzyme linked immunosorbent assay(ABC ELISA).Among the 65 recipients, the urinary MCP 1 concentration was (1278?64)pg/ml in 17 with acute rejection, which was higher than that in 40 clinically stable ones(511?16 pg/ml, P
