SERUM LEPTIN LEVEL IN PREGNANT WOMEN BEFORE DELIVERY AND THEIR NEWBORNS
- VernacularTitle:产前母血及新生儿脐血瘦素水平的测定及其临床意义
- Author:
Ping PENG
;
Wenling LI
;
Yuehu JIANG
- Publication Type:Journal Article
- Keywords:
pregnancy;
leptin;
blood pressure;
fetal blood
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Levels of serum leptin were measured in 150 healthy, 50 PIH pregnant women before the delivery time and their newborns by Immuno radioassay(RIA) method. Serum leptin concentrations were correlated with body weight, body mass index, blood pressure, height of uterus bottom, waist circumference. Results were as follows: ① The serum leptin levels of PIH pregnant women (25 53?1 49?g/L) were significantly higher than those of the normal preghant women (21 13?4 08?g/L). ②The cord serum leptin levels of PIH pregnant women (12 23?4 39?g/L) were significantly higher than those of the normal preghant women (10 29?3 08?g/L). ③The leptin concentrations were positively correlated with body weight, body mass index, height of uterus bottom, waist circumference in the normal pregnant women, but not in the the PIH pregnant women. ④The correlations between leptin concentrations and systolic blood pressure, diastolic blood pressure, medium artery blood pressure in the PIH pregnant women were more obviously significant than those in the normal pregnant women. ⑤The correlations between the maternal serum leptin concentrations and newborns'body weight, body mass index were not significant both in the normal pregnant women and in the PIH pregnant women, however, the maternal serum leptin levels were positively correlated with the cord serum leptin levels in the PIH pregnant women, but not in the normal pregnant women. ⑥The correlations between the leptin levels of umbilical blood and newborns'body weight, body mass index were significant. It is suggested that ①Serum leptin levels of the PIH pregnant women and the neonatal are much higher than those of the normal pregnant women. ②The leptin concentrations of the maternal and the newborn are more correlated with themselves′ fat mass accumulation in the normal pregnant women. ③The cord serum leptin level is regarded as a reliable parameter for evaluating the fetal intrauterine growth. ④The maternal serum leptin level may serve as a marker for monitoring PIH.
