Study on the mechanisms of treating chronic severe hepatitis with plasma exchange
- VernacularTitle:血浆置换治疗慢性重型肝炎
- Author:
Baoyan AN
;
Xiaqiu ZHOU
;
Ruiying GU
- Publication Type:Journal Article
- Keywords:
Plasma exchange;
Hepatocyte growth factor;
Amino acids;
Hepatitis,viral,human
- From:
Chinese Journal of Infectious Diseases
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the mechanisms of plasma exchange(PE) in the treatment of chronic severe hepatitis. Methods Twenty five patients with chronic severe hepatitis were divided into two groups: treatment group and control group. The concentration of ammonia, endotoxin, TNF ?, TGF ? 1, HGF and amino acid spectrum were detected before and after therapy, respectively .Moreover, ammonia and endotoxin levels were detected before and after every treatment with ALSS. Results Compared with the control group ,there were significant decreases in the concentration of ammonia, endotoxin, TNF ?,TGF ? 1 in the treatment group( P