Preliminary report on the influence of HLA classⅡ molecules on outcome of hepatitis B virus infection in Zhejiang district
- VernacularTitle:乙型肝炎病毒感染者人类白细胞抗原的检测
- Author:
Huguang CHEN
;
Guofa JIANG
;
Xueqin MENG
- Publication Type:Journal Article
- Keywords:
Histocempatibilitygens classⅡ;
Allele;
Hepatitis B
- From:
Chinese Journal of Infectious Diseases
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate correlation between HLA classⅡ molecules and the different outcome of viral hepatitis B. Methods Thirty patients with chronic hepatitis B and 56 subjects who had spontaneously recovered from HBV infection in Zhejiang district were enrolled in this investigation. HLA classⅡ molecule types and their alleles were determined by PCR ssp. Results HLA DR12 was found in 21 of 56 subjects recovered from hepatitis B (38%), compared to 3 of 30 patients with chronic hepatitis B (10%, rr 0.19; P corr
