EFFECTS OF 70% HEPATECTOMY ON THE PROLIFERATION OF RAT FETAL HEPATOCYTES AFTER INTRASPLENICAL TRANSPLANTATION
- VernacularTitle:70%肝切除对大鼠胎肝细胞脾内移植后增殖能力的影响
- Author:
Mingzhi YANG
;
Jun MIN
;
Jishen CHEN
- Publication Type:Journal Article
- Keywords:
hepatectomy;
fetal hepatocyte;
transplantation;
spleen;
proliferation
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the effects of 70%Hepatectomy on the proliferation of rat fetal hepatocytes after intrasplenical transplantation, fetal hepatocytes isolated from 3 week SD rat fetuses bred were transplanted into the spleens of liver regeneration model rats with 70% partial hepatectomy. The cell cycle of hepatocytes in the remanent liver was analyzed by flow cytometer and the density dimensions of the donor fetal hepatocytes in spleen were measured by Image Analysis System 7 and 30 days post transplantation respectively. Compared with the control group, the proportions of S state cells in the remanent liver were obviously increased ( P