Bcl-2 AND P53 EXPRESSION IN RENAL CELL CARCINOMA: p53 OVEREXPRESSION IS AN INDEPENDENT PROGNOSTIC PARAMETER
- VernacularTitle:肾癌组织中Bcl-2和P53蛋白的表达:P53是独立的预后指标
- Author:
Xueyou HE
;
Jiangping GAO
;
Yon SONG
- Publication Type:Journal Article
- Keywords:
kidney neoplasms;
P53;
Bcl 2;
immunohistochemistry
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
To elucidate Bcl 2 and P53 protein expression in renal cell carcinoma(RCC) and their patho clinical significance, the expression of Bcl 2 and P53 proteins was evaluated immunohistochemically and compared with the patho clinical factors from 113 patients. The Bcl 2 positivity was demonstrated in 52 cases(46 0%), but no significant correlation with patho clincal factors could be found. 30 cases (26 5%) were positively stained for P53 protein. P53 overexpression was frequently detected in patients with lymphonode or distal metastases ( P =0 047 and P
