GASTROINTESTINAL PRIMARY STROMAL TUMOR IN OMENTUM AND MESENTERY : A CLINICOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY
- VernacularTitle:原发性网膜、肠系膜间质瘤的临床病理及免疫组织化学研究
- Author:
Xiaohong LIU
;
Dalie MA
;
Cenguan BAI
- Publication Type:Journal Article
- Keywords:
stromal tumor;
immunohistochemistry;
C kit;
CD34
- From:
Medical Journal of Chinese People's Liberation Army
1983;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the clinicopathological and immunohistochemical characteristics of omental and mesenteric stromal tumor, 8 cases of stromal tumor were investigated, and followed up. The results showed that these tumors were solitary nodule, most were large. Histologically, cytoplasmic eosinophilia and perinuclear vacuolization were often seen in omental and mesenteric stromal tumor of spindle cell type. 3 cases showed epithelioid cytologic features. An immunohistochemical study showed that all the patients were C kit positive (100%),7 were CD34 positive, whereas 6 were SMA positive, positive expression of p53 and PCNA was found in 2 cases of malignant stromal tumor, Lower expression of PCNA was observed in 1 case of benign one.The results suggested that omental and mesenteric stromal tumors have distinct clinicopathological features, the expression of C kit and CD34 plays an important role in its diagnosis.
