Relationship between hepatic fibrosis and cytokine
- VernacularTitle:肝纤维化与细胞因子的关系
- Author:
Hua WANG
;
Wei WEI
- Publication Type:Journal Article
- Keywords:
hepatic fibrosis;
cytokine
- From:
Chinese Pharmacological Bulletin
1987;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Hepatic fibrosis is a wound healing response to liver injury. Activated hepatic cell is thekey evidence in the pathological fibrosis,which results in synthesis of large quantities of extracellular matrix components. Cytokines secreted mostly by activated Kupffer cell were remarkabe factors which have been proposed to stimulate and inhibit the fibrosis process.The close relationship between hepatic fibrosis and cytokines has been investigated. The article summarizes some important cytokines and the cytokines which can be used as target of antifibrotic therapy.
