Research on intestine permeability in patients with post-hepatitis cirrhosis
- VernacularTitle:病毒性肝炎后肝硬化患者肠道的通透性
- Author:
Hao ZHAO
;
Xiaoou LI
;
Pei WANG
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Intestine permeability;
Diamine oxidase(copper containing);
Lactulose/mannitol ratio
- From:
Chinese Journal of Infectious Diseases
2000;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship of intestine permeability with post hepatitis cirrhosis. Methods Serum DAO levels were measured by Holt method and lactulose/mannitol absorption tests were performed in 96 patients (Child A, n =11; Child B, n =37; Child C n =48) with post hepatitis cirrhosis and 49 healthy control subjects to evaluate the intestine structure and function of the patients. Lactulose and mannitol levels in 5 hours urine were determined by gaschromatographic assay. Results DAO activity and lactulose/mannitol ratio were higher in each patient group than those in normal control group (DAO Child A 4.68?0.97, Child B 6.05?1.02, Child C 7.80?1.34 vs 3.98?0.93, P
