The study of the multiple sclerosis by using MR diffusion-weighted imaging
- VernacularTitle:多发性硬化的MR扩散加权成像研究
- Author:
Hongbin HAN
;
Jingxia XIE
;
Yi LIU
;
Jian LI
;
Ruping XIE
- Publication Type:Journal Article
- Keywords:
Multiple sclerosis;
Demyelinating diseases;
Brain;
Magnetic resonance imaging
- From:
Chinese Journal of Radiology
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize the appearances of MS lesions on DWI, and to quantitatively study the ADC and AI values in different clinical MS subgroups Methods One hundred and eighty seven lesions were studied in 18 cases of MS at different clinical stages Routine MR and DWI were performed in all cases ADC and AI were calculated in the lesions,NAWM, and normal control group Results Hyperintensity (edema like on T 2WI) was demonstrated on DWI at acute primary progressive MS lesions Hyperintense ring sign was found at acute relapse MS lesions ADC increased in all subgroups of MS Significant difference of ADC was demonstrated among MS lesions, NAWM, and normal control groups Significant decrease of AI was demonstrated at later stages Hyperintensity was found in all MS lesions on T 2WI The hyperintensity lesions on DWI had enhanced or non enhanced appearances on CE T 1WI The ADC value of enhanced MS lesions was less than that of the non enhanced lesions ( t =4 19, P 0 05) Conclusion DWI could give quantitative information for different pathological changes in MS lesions of different clinical subgroups Quantitative measurement of diffusion has great potential value in the diagnosis, differential diagnosis, and the prediction of prognosis in MS
