EFFECTS OF LYCIUM BARBARUM POLYSACCHARIDE ON CYTOKINE EXPRESSION IN HUMAN MONOCYTES
- VernacularTitle:枸杞多糖对人单核细胞细胞因子表达的影响
- Author:
Lu GAN
;
Shenghu ZHANG
- Publication Type:Journal Article
- Keywords:
Lycium barbarum polysaccharide;
human peripheral blood mononuclear cells;
interleukin-2;
tumor necrosis factor-?;
gene expression
- From:
Acta Nutrimenta Sinica
1956;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the effects of Lycium barbarum polysaccharide (LBP-X) on IL-2 and TNF-? gene expressions in human peripheral blood mononuclear cells. Methods: RT-PCR (reverse transcription-polymerase chain reaction) was used to detect the gene expressions of IL-2 and TNF-?. Results: LBP-X at 5-40 mg/L upregulated the levels of IL-2 and TNF-? mRNA in human peripheral blood mononuclear cells after optimal time culture. Conclusion: The immunoenhancing effect of Lycium barbarum polysaccharide may be associated with its stimulation of IL-2 and TNF-? gene expressions.
