STUDY ON RELATIONSHIP BETWEEN ras, p16, p53, HELICOBACTER PYLORI AND GASTRIC CARCINOMA
- VernacularTitle:ras、p16、p53和幽门螺杆菌感染与胃癌发生关系的研究
- Author:
Lixin CHEN
;
Liufang CHENG
;
Yunshen YANG
- Publication Type:Journal Article
- Keywords:
genes, ras;
genes, p16;
genes, p53;
Helicobacter pylori;
stomach neoplasms
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Biopsies were randomly taken from 160 patients through endoscopy. Among them 46 patients suffered from chronic superfacial gastritis, 39 patients from chronic atrophic gastritis, 39 patients from gastric ulcer, and 36 patients from gastric cancer. Ras, p16, and p53 genes were analysed with polymerase chain reaction single strand conformation polymorphism (PCR SSCP). Helicobacter pylori (HP) was examined with RUT. Result: ① the positive rates of ras and mutant p53 in gastric cancer were significantly higher than that in gastritis and gastric ulcer( P
