Inflammatory cytokines and Alzheimer disease
- VernacularTitle:炎性细胞因子与阿尔采末病
- Author:
Qingli WANG
;
Gengtao LIU
- Publication Type:Journal Article
- Keywords:
alzheimers disease;
cytokine;
inflammation
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory response clearly occured in pathologically vulnerable regions of the Alzheimers disease (AD) brain. Many proinflammatory mediators, such as IL-1, IL-6,TNF-? and TGF-?, were significantly up-regulated in the pathophysiological process of AD. In addition to their traditional actions as proinflammatory molecules, AD-specific interactions of the cytokines and amyloid ?(A?) may be pathophysiologically relevant, and there was a reciprocal relationship within the cytokines inducing and being induced by A?.
