The change of functions and hypermicro-instructure in lung in experimental aging mice and effect of cistanche desertica polysacchrides on the change
- VernacularTitle:实验性衰老小鼠肺功能和超微结构的变化及肉苁蓉多糖的影响
- Author:
Yun SUN
;
Dejun WANG
;
Xiaomei LIU
;
Le SHI
;
Hongquan ZHANG
- Publication Type:Journal Article
- Keywords:
lung;
aging;
anti-oxydant;
ultra-structure;
cistanche desertica polys acchrides
- From:
Chinese Pharmacological Bulletin
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM To observe the alteration of the functions and hypermicro-instructure in lung of experimental aging mice and the effect of cistanche desertica polysacchrides on the alteration. METHODS To use the models of inhaling ozone (O 3) for 4 week,and two doses of cistanche desertica polysacchrides (50,100 mg?kg -1 ?d -1 ) were ig administrated to small and large dose group mice per day respectively(for 6 week).Then the behavioral and bio-chemical examinations of lung and blood was carried out,and the ultrastructures were observe by the transmission electronic microscopic. RESULTS Compared with aging models,cistanche desertica polysacchrides could significantly prolong the period of non-oxygen ( P