Serum levels of soluble intercellualr adhesion molecule-1 in patients with non-small cell lung cancer and its clinical significance
- VernacularTitle:非小细胞肺癌患者血清可溶性细胞间粘附分子-1的水平及临床意义
- Author:
Minhua SHI
;
Junzhu HU
;
Huacheng HU
- Publication Type:Journal Article
- Keywords:
NSCLC sICAM-1
- From:
Chinese Journal of Practical Internal Medicine
2001;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical significance of serum sICAM-1 level in patients with NSCLC.Methods Sera from 51 cases with different TNM stages of NSCLC were collected and analyzed for concentration of sICAM-1 with Sandwich ELISA method.Results Serum levels of sICAM-1 were significantly higher in NSCLC group than in healthy controls and correlated with the clinical stage of NSCLC cases.Conclusions sICAM-1 could be an important factor which underlies tumor invasion and metastasis and may have a prognostic value in lung cancer.
