Development of tumor promoter testing model with transfected human bronchial epithelial cells harboring c-Ha-ras~(V12G)
- VernacularTitle:人支气管上皮细胞c-Ha-ras~(V12G)基因转染细胞系促癌剂检测模型的建立
- Author:
Tao WU
;
Muquan YIN
- Publication Type:Journal Article
- Keywords:
transfected cell;
tumor promotor;
PMA
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
1 ?mol/L,24 h); (3) With the development of neoplastic transformation, the resistance to terminal differentiation induced by some promoter increased till the promoter became mitogenic. Conclusion: The development of transfected cells provides a powerful and convenient model for detecting potential tumor promoters and research on the mechanisms of promotion tumor.
