Effect of basic fibroblast growth factor on healing of rabbit corneal wound caused by mustard gas
- VernacularTitle:碱性成纤维细胞生长因子促进芥子气角膜损伤修复的实验研究
- Author:
Jiping CAI
;
Weiguo HU
;
Mingxu ZHU
- Publication Type:Journal Article
- Keywords:
mustard gas;
cornea;
eye burns;
fibroblast growth factor,basic
- From:
Academic Journal of Second Military Medical University
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effect of topical administration of basic fibroblast growth factor (bFGF) on healing of rabbit corneal wound caused by mustard gas. Methods: All the corneas of 8 New Zealand white rabbits were injured by liquid mustard at the concentration of 0.2%. One eye of each rabbit was treated with bFGF eye drops 6 times daily, the other eye with 0.25% chloromycetin eye drops as control. Computerized image analyzer was used to calculate the corneal epithelial healing rate. Results: The mean epithelial healing rate in bFGF-treated eyes was (1.276?0.152) mm 2/h, whereas in the control eyes it was (1.094?0.154) mm 2/h. The difference of 2 groups was statistically significant (P
