EXPERIMENTAL STUDY OF REPAIRING MENISCUS INJURY WITH FIBROCHONDROCYTECOLLAGEN CONSTRUCT
- VernacularTitle:纤维软骨细胞-胶原复合物修复半月板损伤的实验研究
- Author:
Yunli ZHU
;
Xin JING
;
Zhih MIAO
- Publication Type:Journal Article
- Keywords:
menisci, tibial;
cell culture;
collagen;
biomedical engineering
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the repairing effect of fibrochondrocyte collagen construct in meniscus lesion, fibrochondrocytes were isolated and expanded in vitro , then seeded onto collagen construct .18 dogs with wedged shape lesion in the lateral meniscus were randomly divided into 3 groups: the lesion were filled with either cell collagen construct or collagen or untreated. The lateral meniscus was then examined grossly and histologically at different periods. The results showed that the lesions that had been filled with fibrochondrocyte collagen construct healed with fibrocartilage tissue. The results suggest that tissue engineering method is practical.