A STUDY OF TUROMBIN APTAMER AS AN ADJUNCT IN ACCELERATING THROMBOLYSIS WITH UROKINASE
- VernacularTitle:凝血酶适配体辅助溶栓及预防再闭塞作用的研究
- Author:
Yingqi LIU
;
Tiande LI
;
Yulong CONG
- Publication Type:Journal Article
- Keywords:
thrombin aptamer;
thrombolytic therapy;
reperfusion;
thrombosis
- From:
Medical Journal of Chinese People's Liberation Army
1982;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
On the basis of superimposed stenosis, a model of femoral occlusive thrombus was produced in 12 dogs. Among them, urokinase+saline were given in 6 dogs (group A), aptamer was given ten minutes before urokinase in another 6(group B). The aim of the study was to explore the effect of a new direct sited thrombin inhibitor thrombin aptamer on thrombolysis . The results showed that the interval between thrombosis and reflow was significantly different between this two groups ( P
