EFFECTS OF RETINOIDS ON THE PRODUCTION OF CYTOKINES OF PBMC FROM THE CHILDREN WITH RECURRENT RESPIRATORY INFECTION
- VernacularTitle:类视黄醇对呼吸道感染患儿细胞因子分泌的影响
- Author:
Junhong ZHANG
;
Youqiong QIAN
;
Deyuan ZHENG
- Publication Type:Journal Article
- Keywords:
retinoids;
recurrent respiratory infection;
interleukin 1;
interleukin 2
- From:
Acta Nutrimenta Sinica
1956;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To study the effects of retinoids (retinol? retinoic acid? retinyl acetate) in vitro on the production of interleukin 1 (IL-1)? interleukin 2 (IL-2) of peripheral blood mononuclear cells (PBMC) from the children with recurrent respiratory infection (RRI). Methods: The activities of IL-1? IL-2 of the PBMC from RRI children and the changes of IL-1? IL-2 activities after cultured with 10 -9 mol/L retinoids were measured. Results: The activities of IL-1? IL-2 of PBMC from RRI children were lower than normal control and could be restored to normal level after cultured with retinoids. Conclusion: The production of IL-1? IL-2 of PBMC from RRI children can be enhanced by retinoids and restored to normal.
