Studies on amino acids in microfilariae of periodic Brugia malayi before and after cytotoxicity
- VernacularTitle:马来丝虫幼虫经细胞毒作用后氨基酸的变化
- Author:
Zheng FANG
;
Yukun SHI
;
Weiqun HUANG
- Publication Type:Journal Article
- Keywords:
Cytotoxicity;
Brugia malayi;
Microfilariae;
Amino acid
- From:
Chinese Journal of Infectious Diseases
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the mechanism of killing microfilariae in host by detecting the change of amino acids in Brugia malayi microfilariae. Methods The composition and contents of amino acid in microfilariae of periodic Brugia malayi before and after the effect of cytotoxicity were analyzed with automatic amino acid analyzer. Results The result showed that microfilariae contained 17 kinds of amino acids, but lacked Tryptophan. The total amount of amino acids of the microfilariae after cytotoxicity was lower than that before cytotoxicity( P
