EXPRESSION AND SIGNIFICANCE OF CD44v6 PROTEIN IN SQUAMOUS CELL CARCINOMA OF THE TONGUE
- VernacularTitle:CD44v6蛋白在舌鳞癌组织中的表达及其意义
- Author:
Jun ZHOU
;
Yong HE
;
Ya JIN
- Publication Type:Journal Article
- Keywords:
tongue neoplasms;
CD44v6 protein;
neoplasms metastasis;
immunohistochemistry
- From:
Medical Journal of Chinese People's Liberation Army
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
To study the expression and significance of CD44 splice variant V6 in squamous cell carcinoma of the tongue. The expression levels of CD44v6 protein were determined immunohistochemically in 40 squamous cell carcinoma of the tongue specimens (24 non metastatic primary tumors and 16 metastatic lymph nodes), 12 squamous cell papilloma and 9 normal tongue mucosa using murine exon V6 specific monoclonal antibody. The CD44v6 overexpression was detectable in 29 of 40 squamous carcinoma of the tongue, in 2 of 12 squamous cell papilloma, in 0 of 9 mormal mucosa, P
