An Overview of Eosinophilic Esophagitis.
- Author:
Hyojin PARK
1
Author Information
- Publication Type:Review
- Keywords: Eosinophilic esophagitis; Gastroesophageal reflux; High-power field
- MeSH: Administration, Topical; Adrenal Cortex Hormones/*therapeutic use; Adult; Child; Deglutition Disorders/etiology; Diagnosis, Differential; Eosinophilic Esophagitis/complications/diagnosis/*therapy; Esophageal Stenosis/etiology/*surgery; Esophagoscopy; Esophagus/*pathology; *Food Habits; Gastroesophageal Reflux/diagnosis; Humans
- From:Gut and Liver 2014;8(6):590-597
- CountryRepublic of Korea
- Language:English
- Abstract: Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease affecting both children and adults. The condition is characterized by an eosinophilic infiltration of the esophageal epithelium. Symptoms of esophageal dysfunction include dysphagia, food impaction and symptoms mimicking gastroesophageal reflux disease. Endoscopic examination typically reveals mucosal fragility, ring or corrugated mucosa, longitudinal furrows, whitish plaques or a small caliber esophagus. Histologic findings of >15 eosinophils per high-power field is the diagnostic hallmark of EoE. An elimination diet, topical corticosteroids or endoscopic dilation for fibrostenotic disease serve as effective therapeutic option.
