Changes of serum thrombopoietin level in patients with aplastic anemia and idiopathic thrombocytopenic purpura.
- VernacularTitle:再生障碍性贫血和特发性血小板减少性紫癜患者血小板生成素的检测及意义
- Author:
Xin DU
;
Mingchun WANG
;
Liping NIE
- Publication Type:Journal Article
- Keywords:
Thrombocytopenia\ Aplastic anemia\ Idiopathic thrombocytopenic purpura\ Thrombopoietin
- From:
Chinese Journal of Practical Internal Medicine
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To measure serum thrombopoietin(TPO)levels in thrombocytopenic conditions of aplastic anemia(AA)and idiopathic thrombocytopenic purpura(ITP)and explore the clinical significance of the changes of TPO levels.Methods Serum TPO concentration was determined in AA(n=13),ITP(n=20)and normal controls(n=17)by using an enzyme linked immunosorbent assay(ELISA).Results Serum TPO level in AA patients was much higher than that in normal controls[(683\^48?414\^73)ng/L vs (99\^41?73\^84)ng/L,P0 05].Furthermore,there was an inverse correlation between TPO concentration and platelet count in AA patients(r=-0\^71,P
