THE CHANGE IN ENERGY CHARGE IN CULTURED HUVECS STIMULATED WITH LPS AFTER TREATMENT WITH FIVE CHINESE MEDICINES
- VernacularTitle:5种药物对内毒素所致培养脐静脉内皮细胞能量代谢的影响
- Author:
Fusheng SHI
;
Guiping DI
;
Zhenggu YANG
- Publication Type:Journal Article
- Keywords:
endotoxins;
endothelium, vascular, umbilical veins;
anisodamine;
salvia miltiorrhiza;
ecdyste rone;
energy metabolism
- From:
Medical Journal of Chinese People's Liberation Army
1981;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
The protective function of five traditional herb medicines, namely anisodamine,escin,salvia miltiorrhizae radix,astragalus root and ecdysterone, in cultured HUVECs challenged by LPS. ATP,ADP,AMP and energy charge were measured in cultured HUVECs challenged by LPS after treatment with five herb medicines. The results showed that energy charge of HUVECs decreased after LPS challenge,and increased significiantly more afer the addition of escin,radix astragali and ecdysterone than other herbs.It suggested that escin, astragalus and ecdysterone can protect HUVECs from injury induced by LPS.
